Relationship between phenotypes of cell-function differentiation and pathobiological behavior of gastric carcinomas

Figure 1 Primary stomach cancer of AFDT with liver metastasis. AKP was moderately positive and distributed along the free edge of cancerous papillary structure. Frozen section. × 20

Figure 2 The same case in Figure 1, Tp53 protein was expressed in most of primary cancer cells. Immunostain, × 16

Figure 3 The same case of Figure 1. CD44v6 was expressed in most of primary cancer cells. Immunostain, × 20

Figure 4 The same case of Figure 1. There was obvious basement membrane like structure with Laminin positive in the primary tumor. Immunostain, × 40

Figure 5 The same case of Figure 1. There was also obvious basement membrane like structure with laminin positive in the liver metastatic tumor. Immunostain, × 20

Figure 6 The same case of Figure 1. CD44v6 was also expressed in the liver metastatic cancer cells. Immunostain, × 20

Figure 7 Primary gastric carcinoma of AMPFDT with ovary metastasis. LAP was moderately positive and distributed in the membrane and cytoplasm of cancer cells. Frozen section, × 40

Figure 8 The same case of Figure 7. Sialomucin and neutral mucin were positive in the primary cancer cells. Mucin histochemistry, × 20

Figure 9 The same case of Figure 7. Most of primary cancer cells expressed ER, which was distributed in the nuclei and cytoplasm. Immunostain, × 20

Figure 10 The same case of Figure 7. LAP was moderately positive in the ovary metastatic cancer cells. Frozen section, × 20

Figure 11 The same case of Figure 7. Sulfomucin was positive in the ovary metastatic cancer cells. Mucin histochemistry, × 40

Figure 12 The same case of Figure 7. Most of the ovary metastatic cancer cells expressed ER. Immunostain, × 40