Anatomical laterality of primary intestinal diffuse large B-cell lymphoma independently stratifies survival: New prognostic nomogram incorporating tumor location

Figure 1 Patient selection flow for primary intestinal diffuse large B-cell lymphoma. A: SEER training cohort; B: Sun Yat-sen University Cancer Center external validation cohort. PI: Primary intestinal; DLBCL: Diffuse large B-cell lymphoma; IPI: International prognostic index.

Figure 2 Overall survival in the SEER cohort. A: Left-sided primary intestinal (PI) diffuse large B-cell lymphoma (DLBCL) vs intra-abdominal nodal DLBCL (N-DLBCL); B: Right-sided PI-DLBCL vs intra-abdominal N-DLBCL.

Figure 3 Overall survival in primary intestinal diffuse large B-cell lymphoma by laterality. A: Pre-propensity score matching; B: Post-propensity score matching.

Figure 4 Multivariable Cox model and nomogram. A: Forest plot; B: Nomogram predicting 1-, 2-, and 3-year overall survival. PSM: Propensity score matching; HR: Hazard ratio; CI: Confidence interval.

Figure 5 Training cohort performance. A: Time-dependent receiver operating characteristic curves (1-, 2-, 3-year); B: 1-year calibration; C: 2-year calibration; D: 3-year calibration. AUC: Area under the curve; OS: Overall survival.

Figure 6 External validation. Receiver operating characteristic comparison of the nomogram vs international prognostic index at: A: 1 year; B: 2 years; C: 3 years. ROC: Receiver operating characteristic; AUC: Area under the curve; IPI: International prognostic index.

Figure 7 Nomogram-based risk stratification. A: SEER training cohort; B: External validation cohort.