Relation between cortisol and metabolic dysfunction-associated steatotic liver disease: A dog chasing its tail

doi:10.3748/wjg.v32.i16.116142

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 32, Issue 16

This Article

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (182)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-1) series, Tables (1-3) series.

Item

Count

PDF

HTML

Figures (1-1)

Tables (1-3)

Sum=138

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=82

Apr 28, 2026 (publication date) through Apr 20, 2026

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Apr 28, 2026; 32(16): 116142
Published online Apr 28, 2026. doi: 10.3748/wjg.v32.i16.116142

Open in New Tab Full Size Figure Download Figure

Figure 1 Role of cortisol in liver metabolism and its metabolic pathways. A: Cortisol is produced upon stimulation by adrenocorticotropic hormone. In the liver, it enhances gluconeogenesis, fatty acid absorption, and lipogenesis, thereby increasing the risk of liver steatosis; B: Cortisone is metabolized by 11β-hydroxysteroid dehydrogenase type 1 into cortisol, and by 5α-reductase and 5β-reductase into inactive metabolites. ACTH: Adrenocorticotropic hormone; FA: Fatty acid; 11β-HSD1: 11β-hydroxysteroid dehydrogenase type 1; 5α-R: 5α-reductase; 5β-R: 5β-reductase.

Citation: Morgante C, Camma C, Petta S, Guarnotta V, Arnaldi G. Relation between cortisol and metabolic dysfunction-associated steatotic liver disease: A dog chasing its tail. World J Gastroenterol 2026; 32(16): 116142
URL: https://www.wjgnet.com/1007-9327/full/v32/i16/116142.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i16.116142