Letter to the Editor: Balancing efficacy and toxicity: The critical role of predictive models in colorectal cancer chemotherapy

doi:10.3748/wjg.v32.i15.116121

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Apr 21, 2026; 32(15): 116121
Published online Apr 21, 2026. doi: 10.3748/wjg.v32.i15.116121

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Figure 1 Integrated efficacy-toxicity framework for precision first-line colorectal cancer chemotherapy. CA19-9: Carbohydrate antigen 19-9; CA125: Carbohydrate antigen 125; KRAS: Kirsten rat sarcoma viral oncogene homolog; BRAF: B-Raf proto-oncogene: Serine/threonine kinase; TP53: Tumor protein p53; UGT1A1: UDP glucuronosyltransferase family 1 member A1; GSTM1: Glutathione S-transferase mu 1; ABCC2: ATP-binding cassette subfamily C member 2; CYP3A5: Cytochrome P450 family 3 subfamily A member 5; GSTP1: Glutathione S-transferase pi 1; CRC: Colorectal cancer.

Citation: Qin YW, Li PW, Liang XY, Mo Y, Chen DW. Letter to the Editor: Balancing efficacy and toxicity: The critical role of predictive models in colorectal cancer chemotherapy. World J Gastroenterol 2026; 32(15): 116121
URL: https://www.wjgnet.com/1007-9327/full/v32/i15/116121.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i15.116121