Lymph node metastatic patterns of gastric carcinoma with a combination of adenocarcinoma and neuroendocrine carcinoma components

Figure 1 Lymph node metastasis pattern of adenoneuroendocrine mixed gastric cancer. A: The components of lymph node metastasis are purely neuroendocrine carcinoma; B: The components of lymph node metastasis are purely adenocarcinoma; C: Different lymph nodes metastasize different components; D: The same lymph node contains both neuroendocrine carcinoma and adenocarcinoma metastatic components.

Figure 2 Violin plot analysis of neuroendocrine carcinoma proportions and lymph node metastasis components probabilities in adenoneuroendocrine mixed gastric cancer. The violin plot illustrates the fluctuating proportions of neuroendocrine carcinoma in the primary lesion of adenoneuroendocrine mixed gastric cancer, as well as the probabilities associated with different lymph node metastatic components. NEC: Neuroendocrine carcinoma; AC: Adenocarcinoma; LN: Lymph node.

Figure 3 Kaplan-Meier curves. A: Kaplan-Meier curves for lymph node periosteal violation and overall survival; B: Kaplan-Meier curves for lymph node periosteal violation and disease-free survival; Kaplan-Meier cumulative survival curves according to overall tumour survival of neuroendocrine carcinoma%: C: Primary tumour; D: Histological type; E: Lauren type; F: Comparison of overall survival in three patterns of lymph node metastasis; G: Comparison of overall survival in lymph node metastasis comprising “pure” adenocarcinoma and “pure” neuroendocrine carcinoma. OS: Overall survival; DFS: Disease-free survival; NEC: Neuroendocrine carcinoma; AC: Adenocarcinoma; LN: Lymph node.