Irritable bowel syndrome remains a complex disorder of gut-brain interaction: Too many actors on stage

doi:10.3748/wjg.v31.i8.101357

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Feb 28, 2025 (publication date) through Jan 23, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2025; 31(8): 101357
Published online Feb 28, 2025. doi: 10.3748/wjg.v31.i8.101357

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Figure 1 The microbiota-gut-brain axis. The microbiota-gut-brain axis denotes the bidirectional communications between the central nervous system, the enteric nervous system, the gastrointestinal system, and the gut microbiota. This intricate interplay, when disrupted, underpins many of the pathophysiological elements underlying irritable bowel syndrome (IBS). 5-HT: Serotonin; SCFAs: Short-chain fatty acids.

Citation: Pellegrino R, Gravina AG. Irritable bowel syndrome remains a complex disorder of gut-brain interaction: Too many actors on stage. World J Gastroenterol 2025; 31(8): 101357
URL: https://www.wjgnet.com/1007-9327/full/v31/i8/101357.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i8.101357