Peripheral blood lymphocyte subset deficiency in acute-on-chronic liver failure and reconstitution following liver transplantation

Figure 1 Characteristics of peripheral blood lymphocyte subsets. A: Characteristics of peripheral blood lymphocyte subsets (PBLSs) among healthy volunteers and the disease groups; B: Characteristics of PBLSs with increasing severity of acute-on-chronic liver failure. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001. CD: Cluster of differentiation; HV: Healthy volunteer; ACLF: Acute-on-chronic liver failure; AD: Acute decompensation; NK: Natural killer.

Figure 2 Kaplan-Meier survival curve for patients with acute-on-chronic liver failure. ACLF: Acute-on-chronic liver failure.

Figure 3 Dynamic changes of peripheral blood lymphocyte subsets before and after liver transplantation in patients with acute-on-chronic liver failure. The number of patients at pre-liver transplantation (LT), post-LT days 14, and post-LT days 21 were 38, 33, and 23, respectively. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. CD: Cluster of differentiation; LT: Liver transplantation; NK: Natural killer.