Beyond the gluten-free diet: Innovations in celiac disease therapeutics

doi:10.3748/wjg.v30.i38.4194

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Oct 14, 2024 (publication date) through Oct 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2024; 30(38): 4194-4210
Published online Oct 14, 2024. doi: 10.3748/wjg.v30.i38.4194

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Figure 1 Mechanistic insights into innovative therapeutic approaches for celiac disease. APC: Antigen-presenting cell; IELs: Intraepithelial lymphocytes; IFN: Interferon; IL: Interleukin; MMP: Matrix metalloproteinase; pDC: Pre-dendritic cell; tTG: Tissue transglutaminase; TNF: Tumor necrosis factor.

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Figure 2 Emerging therapeutic strategies from Phase 2 trials in celiac disease treatment. CCR9: C-C chemokine receptor type 9; IL: Interleukin; JAK3: Janus kinase 3.

Citation: Massironi S, Franchina M, Elvevi A, Barisani D. Beyond the gluten-free diet: Innovations in celiac disease therapeutics. World J Gastroenterol 2024; 30(38): 4194-4210
URL: https://www.wjgnet.com/1007-9327/full/v30/i38/4194.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i38.4194