Impact of preoperative antibiotics and other variables on integrated microbiome-host transcriptomic data generated from colorectal cancer resections

Figure 1 Principal coordinate analysis plots for Morita Horn dissimilarity indices. A: Preoperative antibiotic treatment (yes/no); B: Tumor vs nontumor histology; C: Anatomic location of sample (left vs right); D: Diabetes mellitus status (yes/no); E: Black/African Ancestry race (yes/no). The filled circles and surrounding ovals indicate the mean ± SD centroid for each group.

Figure 2 Scatter plots of threshold cycle values. A: Fusobacterium nucleatum nusG gene; B: Broad range 16S rRNA gene; C: Human SLCOA2 gene quantitative polymerase chain reaction assays. F. nucleatum: Fusobacterium nucleatum.

Figure 3  Principal coordinate analysis of human colorectal cancer RNA-seq data with respect to tumor histology (tumor vs nontumor) and preoperative antibiotics (yes/no).