Golimumab in real-world practice in patients with ulcerative colitis: Twelve-month results

Figure 1 Overview of mean work productivity and activity impairment (WPAI) domain scores comparison vs baseline in patients employed at baseline (employed analysis population). A: Patients with absenteeism; B: Patients with presenteeism; C: Patients‘ work impairment; D: Patients’ activity impairment. Bars represent the standard deviation. A significant reduction in all work productivity and activity impairment sub-scores after onset of golimumab therapy was detectable for each time point in comparison to baseline (for each visit P < 0.0001, Wilcoxon signed rank test). UC: Ulcerative colitis; BL: Baseline; n: Number of patients; SD: Standard deviation.

Figure 2 Inflammatory bowel disease questionnaire (IBDQ) score – change from baseline over time (total analysis population). The difference from baseline in the total IBDQ score was statistically significant for all visits (^aP < 0.0001, Wilcoxon signed rank test). Standard deviation is given in brackets.

Figure 3 Short form-12 health survey questionnaire - physical component score (PCS-12) and short form-12 health survey questionnaire - mental component score (MCS-12) – change from baseline over time (total analysis population). The difference from baseline in the PCS-12 as well as in the MCS-12 was statistically significant for all visits (^aP < 0.0001, Wilcoxon signed rank test). Standard deviation is given in brackets. PCS-12: Short form-12 health survey questionnaire - physical component score; MCS-12: Short form-12 health survey questionnaire - mental component score.