Δ4-3-oxosteroid-5β-reductase deficiency: Responses to oral bile acid therapy and long-term outcomes

doi:10.3748/wjg.v25.i7.859

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Feb 21, 2019 (publication date) through Feb 18, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2019; 25(7): 859-869
Published online Feb 21, 2019. doi: 10.3748/wjg.v25.i7.859

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Figure 1 Typical negative ion fast atom bombardment ionization mass spectrometry spectrum of a patient with ∆4-3-oxosteroid 5β-reductase deficiency before and after treatment with bile acids. AKR1D1: Δ4-3-oxosteroid 5β-reductase; CDCA: Chenodeoxycholic acid; UDCA: Ursodeoxycholic acid.

Citation: Zhang MH, Setchell KD, Zhao J, Gong JY, Lu Y, Wang JS. Δ4-3-oxosteroid-5β-reductase deficiency: Responses to oral bile acid therapy and long-term outcomes. World J Gastroenterol 2019; 25(7): 859-869
URL: https://www.wjgnet.com/1007-9327/full/v25/i7/859.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i7.859