Relationship between response to lusutrombopag and splenic volume

Figure 1 Axial computed tomography section (A) and reconstructed 3-D image (B) of the spleen. The volume measurement was performed using virtual organ computer-aided analysis on enhanced computed tomography in an enrolled patient with splenomegaly. The total volume was 1212 mL calculated using the software.

Figure 2 Mean changes in platelet count in all patients with splenomegaly treated with 3. 0 mg/d lusutrombopag for 7 d. Data are expressed as the mean ± SD. The paired t-test was used to compare paired data. Max: The maximum count.

Figure 3 Correlation between change in platelet count and splenic size in patients with cirrhosis. Correlation was determined using Pearson’s r coefficient. Data are expressed as the mean ± SD.

Figure 4 Receiver-operating characteristic curve for splenic size and the area under the curve.