Efficacy of thalidomide therapy in pediatric Crohn’s disease with evidence of tuberculosis

Figure 1 Changes in pediatric Crohn’s disease activity index before and after 9-12 mo of thalidomide treatment in 10 patients. There was a decrease of the pediatric CD activity index (PCDAI) scores in 9 patients (P < 0.05), 6 of them achieved clinical remission (PCDAI < 10). PCDAI: Pediatric Crohn’s disease activity index.

Figure 2 Changes of laboratory indices before and after 9-12 mo treatment in 10 Crohn’s disease patients with tuberculosis. A: Erythrocyte sedimentation rate (ESR); B: C-reactive protein (CRP); C: Hemoglobin (Hb); D: Platelet (PLT). It showed significant reductions in ESR, CRP and platelet levels (P < 0.05); and an increasing trend in Hb levels.

Figure 3 Changes in weight for age Z score before and after 9-12 mo treatment in 10 cases treated with thalidomide.