Spontaneous rupture of hepatic epithelioid hemangioendothelioma: A case report

Figure 1 Computer tomography. A: Venous phase image revealed multiple low-density intrahepatic nodules in both lobes, and part of nodules showed inhomogeneous enhancement; B: The maximum lesion was located in the right lobe under the hepatic capsule; C: Computer tomography scan after transcatheter arterial embolization revealed massive hematocoelia.

Figure 2 Histopathologic findings of hepatic epithelioid hemangioendothelioma. Carcinoma cells appeared nest-like or papillary around the blood vessels, the nuclei were round or ovoid (hematoxylin-eosin staining; magnification × 200).

Figure 3 Immunohistochemical examination of hepatic epithelioid hemangioendothelioma. A: Specimen stained positive for CD31 (magnification × 200); B: Specimen stained positive for CD34 (magnification × 200); C: Specimen stained positive for FVIII (magnification × 200); D: Ki-67 proliferation index is less than 40% (magnification × 100).