Ultrastructural observation of Helicobacter pylori to the gastric epithelia in chronic gastritis and peptic ulcers

Figure 1 The bacillus abuts upon the depression of the plasma membrane (*) of the vacuolated cell. ( × 21000)

Figure 2 The bacilli (*) penetrating deep in between the mucous cells. The tight junction was broken and the intercellular space was dilated. ( × 21000)

Figure 3 The bacillus shows the first step of adherence initiated by the direct contact of the organism to the microvilla glycocalyx. ( × 28500)

Figure 4 A great number of bacteria grouped in a colony shown with periplasmic pools (s). The bacilli abutting upon the depression of the plasma membrane of mucous neck cells lost microvilli and vacuolated. ( × 8700)

Figure 5 Neutrophils (*) penetrated into the epithelia and migrated to the bacilli located in the apical region of mucous neck cells. ( × 10800)

Figure 6 The bacillus is phagocytized by neutrophils located in the lumen. In the phagosome, two lysosomes approach the bacillus, of which the cell wall was lysed and discontinuous. ( × 43500)