Review
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 7, 2012; 18(9): 882-888
Published online Mar 7, 2012. doi: 10.3748/wjg.v18.i9.882
Figure 1
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Figure 1 DNA methylation machinery. NLS: Nuclear localization signal; PCNA: Proliferating cell nuclear antigen.
Figure 2
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Figure 2 Proteins that bind the methylated DNA. MBD: Methylation-binding protein; TRD: Transcription repression domains.
Figure 3
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Figure 3 How methylation represses the gene expression. .
Figure 4
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Figure 4 Factors for cancer development. LOH: Heterozygosity; MSI: Microsatellite instability.