Anticoagulation therapy prevents portal-splenic vein thrombosis after splenectomy with gastroesophageal devascularization

Figure 1 Changes in platelet count and prothrombin time/international normalized ratio in group A and group B. It was not different in platelet (PLT) between the two groups (P = 0.981), but it was statistically different in prothrombin time/international normalized ratio (PT/INR) between the two groups (P = 0.020). PT/INR in group A had no sequential changes pre- and post-operatively (P = 0.479) and PT/INR in group B was increasing gradually from postoperative day 7 with statistical difference (P = 0.003). POD: Postoperative day.

Figure 2 Changes in prothrombin time/international normalized ratio in patients without portal or splenic vein thrombosis and portal or splenic vein thrombosis. In group A, patients with or without portal or splenic vein thrombosis (PSVT) had similar prothrombin time/international normalized ratio (PT/INR), and the difference was not significant between the two subgroups. Patients with or without PSVT presented different PT/INR only at day 14 after surgery, with statistical significance (1.23 ± 0.17 vs 1.30 ± 0.21, P = 0.037) by Student’s t test. In group B, patients with or without PSVT had different PT/INR only at day 14 after surgery, with statistical significance (1.18 ± 0.14 vs 1.28 ± 0.21, P = 0.017) by Student’s t test. POD: Postoperative day.