Cell proliferation of esophageal squamous epithelium in erosive and non-erosive reflux disease

Figure 1 Study profile. RT-PCR: Reverse transcription polymerase chain reaction; NERD: Non-erosive reflux disease; ERD: Erosive reflux disease.

Figure 2 Cytological preparation from esophageal biopsy after epithelial cell isolation. Only epithelial cells were present. Toluidine blue staining (300 ×).

Figure 3 Box plots of relative expression of cyclin D1 mRNA by real-time RT-PCR analysis; median (bold line in box), and interquartile range (upper and lower lines of the box) in human esophageal mucosa of NERD and ERD patients (P < 0. 01). RT-PCR: Reverse transcription polymerase chain reaction; NERD: Non-erosive reflux disease; ERD: Erosive reflux disease.

Figure 4 Box plots of relative expression of cyclin A mRNA by real-time RT-PCR analysis values; median (bold line in box), and interquartile range (upper and lower lines of the box) in human esophageal mucosa of NERD and ERD patients. RT-PCR: Reverse transcription polymerase chain reaction; NERD: Non-erosive reflux disease; ERD: Erosive reflux disease.

Figure 5 Box plots of BrdU-LI analysis values, median (bold line in the box), and interquartile range (upper and lower lines of the box) in human esophageal mucosa of NERD and ERD patients. NERD: Non-erosive reflux disease; ERD: Erosive reflux disease.