Biochemical metabolic changes assessed by 31P magnetic resonance spectroscopy after radiation-induced hepatic injury in rabbits

Figure 1 Orientation of CSI: the location of VOI of three voxels being selected in the largest section of rabbit liver on MRI with true FISP sequence.

Figure 2 ³¹P magnetic resonance spectrum from a 500 mL phosphate (NaH₂PO₄) solution phantom with 0. 05 mol/L concentrations.

Figure 3 Hepatic ³¹P MRS of the liver from a rabbit of the control group (A), mild injury group (B), moderate injury group (C) and severe injury group (D). A significant decrease in the ATP signal is seen in the ³¹P MR spectra (C, D).

Figure 4 Representative histological section of the liver from a rabbit of the control group (A), mild injury group (B), moderate injury group (C) and severe injury group (D). I: Integral.

Figure 5 The graph shows the correlation between LDS and ATP, that is, the ATP relative quantification decreases progressively with the increase of LDS.