A case of gallbladder carcinoma associated with pancreatobiliary reflux in the absence of a pancreaticobiliary maljunction: A hint for early diagnosis of gallbladder carcinoma

Figure 1 A: CT reveals diffuse thickening of the gallbladder wall and dilatation of the common bile duct to 14 mm; B: After 42 mo, CT reveals progressive thickening of the gallbladder wall, suspicious for gallbladder carcinoma.

Figure 2 A: ERCP shows no pancreaticobiliary maljunction, because sphincter of Oddi affected pancreaticobiliary junction and connection between pancreatic and biliary ducts was not visible during the contraction phase of sphincter of Oddi; B: ERCP in the relaxation phase of sphincter of Oddi shows the length of the common channel to be 5 mm long.

Figure 3 Histopathologic examination of the resected specimen demonstrates a moderately differentiated adenocarcioma of the gallbladder (HE stain, × 40).