Expression of CD86 and increased infiltration of NK cells are associated with Helicobacter pylori-dependent state of early stage high-grade gastric MALT lymphoma

Figure 1 Examples of immunohistochemical analysis of CD86 and CD56 (+) NK on B-cells of high-grade gastric MALT lymphoma. A: H pylori-dependent case (case 4) shows positive staining for CD86; B: H pylori-independent case (case 18) shows negative staining for CD86; C: H pylori-dependent case (case 8) carries a larger proportion of CD56 (+) NK cells; D: H pylori-independent case (case 5) contains a lower proportion of CD56 (+) NK cells. Original magnification, ×400.

Figure 2 (PDF) Histograms showing the mean percentage (±SD) of cells staining CD56 (+) NK in H pylori-dependent and H pylori-independent high-grade gastric MALT lymphomas (2. 8±1.4% vs 1.1±0.8%; P = 0.003).