Head-to-head comparison of H2-receptor antagonists and proton pump inhibitors in the treatment of erosive esophagitis: A meta-analysis

Figure 1 Healing-time curve of esophagitis in patients treated with H₂RA. Statistical significance was achieved at 4, 8, and 12 wk, indicating that high dose H₂RAs achieved significantly better healing rates for erosive esophagitis than standard dose H₂RAs.

Figure 2 Healing-time curve of esophagitis in patients treated with standard doses of proton pump inhibitors vs H₂RAs. At wk 2, 4, 8, proton pump inhibitors significantly healed more patients than did H₂RAs.

Figure 3 Healing-time curve of esophagitis in patients treated with standard dose of the newer proton pump inhibitors vs omeprazole. No significant difference in the pooled healing rates between the newer proton pump inhibitors and omeprazole was observed.