Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 28, 2026; 32(48): 122776
Published online Dec 28, 2026. doi: 10.3748/wjg.122776
Published online Dec 28, 2026. doi: 10.3748/wjg.122776
Textbook outcome as a predictor of long-term prognosis in ampullary cancer: A retrospective cohort study
Xin-Yi Guo, Jing-Zhao Zhang, Tong Guo, Xiao-Rui Huang, Deng-Sheng Zhu, Zhen Zhang, Huan Zheng, Ya-Hong Yu, Zhi-Wei Zhang, Division of Hepato-Pancreato-Biliary Surgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430000, Hubei Province, China
Co-corresponding authors: Ya-Hong Yu and Zhi-Wei Zhang.
Author contributions: Zhang ZW, Yu YH, and Guo XY contributed to the conceptualization; Zhang JZ and Huang XR participated in the methodology of the manuscript and the formal analysis; Guo XY was involved in data curation, and contributed to writing original draft; Zheng H, Zhang Z, and Zhu DS contributed to the investigation; Zhang ZW and Yu YH took part in supervision as co-corresponding authors; Zhang ZW and Guo T contributed to funding acquisition. All authors have read and approved the final manuscript.
AI contribution statement: AI tools (specifically ChatGPT) was used solely for linguistic refinement, grammar checking, and formatting assistance during manuscript preparation. No AI tool was used to generate research data, perform statistical analyses, interpret results, or formulate scientific conclusions. All AI-assisted outputs were critically reviewed, verified, and revised by the authors, who take full responsibility for the final content of the manuscript.
Institutional review board statement: The study was reviewed and approved by the Tongji Hospital Institutional Review Board, No. TJ-IRB202510069.
Informed consent statement: As the study used only retrospectively collected, de-identified clinical data and involved no additional interventions, the requirement for written informed consent was waived by the Ethics Committee in accordance with Chinese legislation.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The data underlying this article will be shared on reasonable request to the corresponding author.
Corresponding author: Zhi-Wei Zhang, Division of Hepato-Pancreato-Biliary Surgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430000, Hubei Province, China. zhiweizhang@tjh.tjmu.edu.cn
Received: April 28, 2026
Revised: June 18, 2026
Accepted: June 29, 2026
Published online: December 28, 2026
Processing time: 189 Days and 20 Hours
Revised: June 18, 2026
Accepted: June 29, 2026
Published online: December 28, 2026
Processing time: 189 Days and 20 Hours
Core Tip
Core Tip: This retrospective cohort study of 347 patients with ampullary cancer demonstrated that achieving textbook outcome (TO) following pancreaticoduodenectomy was associated with improved long-term survival. Additionally, propensity score matching revealed no statistically significant difference in TO achievement between the laparoscopic and open approaches. Given its dual value as both a comprehensive perioperative quality metric and long-term prognostic indicator, enhancing TO achievement rates should be prioritized as a central objective in pancreaticoduodenectomy-specific quality improvement initiatives.