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World J Gastroenterol. Dec 28, 2026; 32(48): 122494
Published online Dec 28, 2026. doi: 10.3748/wjg.122494
Published online Dec 28, 2026. doi: 10.3748/wjg.122494
Prevalence, familial clustering, and influencing factors of Helicobacter pylori infection in Western Fujian Province households
Bi-Qin Lin, Shui-Fen Ye, Si-Min Zou, Long-Lu Wang, Li-Ming Tang, Chun-Mei Huang, Wei-Kun Huang, Wei-Wei Deng, Dong-Qin Lai, Xiao-Li Li, Ting Qiu, Han-Zhong Qiu, Mei-E Zeng, Department of General Practice, Longyan First Affiliated Hospital of Fujian Medical University, Longyan 364000, Fujian Province, China
Cun-Lan Luo, Department of General Practice, Longyan People’s Hospital, Longyan 364000, Fujian Province, China
Co-first authors: Bi-Qin Lin and Shui-Fen Ye.
Author contributions: Lin BQ, Zou SM, and Zeng ME conceived and designed the study; Lin BQ and Zou SM searched and screened the related literature; Ye SF, Wang LL, Luo CL, Huang CM, Deng WW, Lai DQ, Li XL, and Qiu T performed data collection; Zeng ME performed a quality assessment; Lin BQ and Zeng ME analyzed the data and explained the outcomes; Lin BQ, Ye SF, Zou SM, Wang LL, Tang LM, Huang CM, Luo CL, Huang WK, Deng WW, Lai DQ, Li XL, Qiu T, Qiu HZ, Zeng ME read and approved the final version of the manuscript to be published.
AI contribution statement: AI tools (specifically ChatGPT) were used solely for linguistic refinement and formatting assistance. No AI tool was involved in the generation of research data, interpretation of results, or formulation of conclusions. All AI-generated outputs were critically reviewed and revised by the authors.
Supported by Longyan City Science and Technology Plan Project China, No. 2023 LYF17040.
Institutional review board statement: This study was reviewed and approved by the Medical Ethics Committee of the Longyan First Affiliated Hospital of Fujian Medical University (No. LYREC2024-k019-01).
Informed consent statement: All participants voluntarily participated in the study and provided written informed consent.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
STROBE statement: The authors have read the STROBE Statement—a checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-a checklist of items.
Data sharing statement: No additional data are available.
Corresponding author: Mei-E Zeng, MD, Doctor, Department of General Practice, Longyan First Affiliated Hospital of Fujian Medical University, No. 105 Jiuyi Bei Road, Xinluo District, Longyan 364000, Fujian Province, China. 957900060@qq.com
Received: April 21, 2026
Revised: June 29, 2026
Accepted: July 28, 2026
Published online: December 28, 2026
Processing time: 196 Days and 23.3 Hours
Revised: June 29, 2026
Accepted: July 28, 2026
Published online: December 28, 2026
Processing time: 196 Days and 23.3 Hours
Core Tip
Core Tip: Current research on the familial clustering of Helicobacter pylori (H. pylori) infection, its prevalence (particularly among minors), and its influencing factors remains limited, with no reported studies in Western Fujian Province. This study identified an overall H. pylori infection rate of 34.0% in Western Fujian Province, including 34.5% among adults and 31.1% among minors. H. pylori infection was associated with household hygiene practices and individual dietary hygiene behaviors, and familial clustering of H. pylori was observed. These findings suggest that family-based prevention and control strategies may be more effective for managing H. pylori infection.