Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 21, 2026; 32(47): 122370
Published online Dec 21, 2026. doi: 10.3748/wjg.122370
Published online Dec 21, 2026. doi: 10.3748/wjg.122370
Incidence of colorectal cancer and advanced polyps by post-polypectomy surveillance interval: Real-world evidence from Thailand
Napat Pongprasobchai, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Krung Thep Maha Nakhon, Thailand
Chayanis Kositamongkol, Euarat Mepramoon, Pochamana Phisalprapa, Division of Ambulatory Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Krung Thep Maha Nakhon, Thailand
Author contributions: Pongprasobchai N, Kositamongkol C and Phisalprapa P designed the study; Pongprasobchai N, Kositamongkol C and Mepramoon E collected the data; Pongprasobchai N, Kositamongkol C and Phisalprapa P analyzed and interpreted the data; Pongprasobchai N, Kositamongkol C and Phisalprapa P performed statistical analysis; Phisalprapa P supervised the study; Mepramoon E served as administrator and provided technical, or material support; Pongprasobchai N and Kositamongkol C performed the manuscript preparation; Pongprasobchai N, Kositamongkol C, Mepramoon E and Phisalprapa P participated in the review and editing; All authors have read and approved the final manuscript.
AI contribution statement: Portions of this manuscript were edited using AI tools (Perplexity) solely for language refinement. The authors carefully reviewed and verified all AI-assisted outputs and take full responsibility for the scientific content of the manuscript.
Institutional review board statement: The study was reviewed and approved by the institutional review board at the Faculty of Medicine Siriraj Hospital, Mahidol University (Certificate of Approval number: Si 104/2024).
Informed consent statement: The informed consent was waived because of the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Data sharing statement: The data that support the findings of this study are available from the corresponding author upon reasonable request.
Corresponding author: Pochamana Phisalprapa, MD, PhD, Associate Professor, Lecturer, Senior Researcher, Division of Ambulatory Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Siriraj, Bangkok Noi, Bangkok 10700, Krung Thep Maha Nakhon, Thailand. pochamana.phi@mahidol.ac.th
Received: April 17, 2026
Revised: May 26, 2026
Accepted: July 10, 2026
Published online: December 21, 2026
Processing time: 193 Days and 22.6 Hours
Revised: May 26, 2026
Accepted: July 10, 2026
Published online: December 21, 2026
Processing time: 193 Days and 22.6 Hours
Core Tip
Core Tip: This 12-year retrospective cohort study provided real-world evidence to optimize post-polypectomy surveillance in resource-limited settings. Analyzing 2875 Thai patients, we found that high-risk patients require surveillance every 2-3 years to minimize colorectal cancer risk. While, low-risk patients may safely extend surveillance intervals to 7-8 years unless new symptoms arise. Tailoring surveillance by risk group offers a viable strategy to maximize endoscopic capacity without compromising patient safety, providing a practical framework for low- and middle-income countries to improve colorectal cancer prevention outcomes.