Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 7, 2026; 32(41): 120954
Published online Nov 7, 2026. doi: 10.3748/wjg.120954
Cancer therapy-induced intestinal injury: Mechanisms, clinical manifestations, and management strategies
Yang-Long Nan, Tuan-He Sun, Kai-Jie Ren, Tian-Hao Min, Yu-Yi Ma, Xin Xie, Xiao-Yuan Deng, Yuan-Chang Peng, Yuan-Yuan Liu, Shi-Yao Tong, Wei Wang, Cheng-Xue Dang, Hao Zhang
Yang-Long Nan, Tuan-He Sun, Kai-Jie Ren, Tian-Hao Min, Yu-Yi Ma, Xiao-Yuan Deng, Yuan-Chang Peng, Yuan-Yuan Liu, Shi-Yao Tong, Cheng-Xue Dang, Hao Zhang, Department of Surgical Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
Tuan-He Sun, State Key Laboratory of Electrical Insulation and Power Equipment, School of Electrical Engineering, Xi’an Jiaotong University, Xi’an 710049, Shaanxi Province, China
Xin Xie, Department of Nuclear Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710000, Shaanxi Province, China
Wei Wang, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
Co-corresponding authors: Cheng-Xue Dang and Hao Zhang.
Author contributions: Nan YL wrote the original draft and contributed to visualization; Sun TH contributed to the discussion and design of the manuscript; Ren KJ, Min TH, Ma YY, Xie X, Deng XY, Peng YC, Liu YY, Tong SY, Wang W, Dang CX, and Zhang H reviewed and edited the manuscript; Ren KJ and Ma YY contributed to the visualization; Dang CX and Zhang H jointly conceptualized the study, supervised the work, and acquired funding, contributing equally as co-corresponding authors. All authors have read and approved the final manuscript.
AI contribution statement: AI tools (ChatGPT) were used during the revision process solely for language polishing and translation. No portion of the main text (including Abstract, Introduction, Main body, Discussion, and Conclusion) was generated by AI. We assure that the study design, selection of the review topic, and structure of the manuscript were entirely conducted by the authors. We confirm that all figures were created by the authors using BioRender, without any AI generation. All AI-generated outputs were critically reviewed and revised by the authors.
Supported by National Social Science Fund of China, No. 23BRK014.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Hao Zhang, MD, Department of Surgical Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, No. 227 Yanta West Road, Xi’an 710061, Shaanxi Province, China.
hao.zhang@mail.xjtu.edu.cn
Received: March 18, 2026
Revised: May 3, 2026
Accepted: June 29, 2026
Published online: November 7, 2026
Processing time: 187 Days and 1 Hours
