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World J Gastroenterol. Oct 7, 2026; 32(37): 119553
Published online Oct 7, 2026. doi: 10.3748/wjg.119553
Published online Oct 7, 2026. doi: 10.3748/wjg.119553
Recommendations for chronic atrophic gastritis research: Highlighting sex-related factors, gastric microbiota, and in-depth mechanistic validation
Fang-Yue Xu, Chang-Hong Wu, The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China
Hai-Tao Chen, Department of Oncology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Xinhua Hospital of Zhejiang Province, Hangzhou 310005, Zhejiang Province, China
Co-first authors: Fang-Yue Xu and Chang-Hong Wu.
Author contributions: Xu FY wrote the original draft; Wu CH contributed to the initial manuscript editing; Chen HT contributed to conceptualization and critical revisions; All authors have read and approved the final manuscript. Xu FY and Wu CH contributed equally to this work as co-first authors.
Conflict-of-interest statement: The authors declare no conflict of interest.
Corresponding author: Hai-Tao Chen, PhD, Department of Oncology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Xinhua Hospital of Zhejiang Province, No. 318 Chaowang Road, Hangzhou 310005, Zhejiang Province, China. 546675503@qq.com
Received: February 2, 2026
Revised: February 14, 2026
Accepted: March 4, 2026
Published online: October 7, 2026
Processing time: 214 Days and 3 Hours
Revised: February 14, 2026
Accepted: March 4, 2026
Published online: October 7, 2026
Processing time: 214 Days and 3 Hours
Core Tip
Core Tip: Recently, several studies on chronic atrophic gastritis (CAG) have demonstrated the significant therapeutic efficacy of traditional Chinese medicine (TCM). Based on recent advances, it is necessary to emphasize the importance of sex-related factors and the gastric microbiota detection in CAG research, as well as to further improve mechanism research with more sufficient experimental evidence in TCM studies.