Pancreatic cancer: Recent epidemiological trends and risk determinants

doi:10.3748/wjg.119810

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Aug 21, 2026; 32(31): 119810
Published online Aug 21, 2026. doi: 10.3748/wjg.119810

Pancreatic cancer: Recent epidemiological trends and risk determinants

Amit Hudgi, Alexander Woodcock, Ali Mirza, Porsha Okiye, Brendan Kemple, Humberto Sifuentes, Subbaramia Sridhar

Amit Hudgi, Humberto Sifuentes, Subbaramia Sridhar, Department of Gastroenterology, Medical College of Georgia/Augusta University, Augusta, GA 30912, United States

Alexander Woodcock, Ali Mirza, Porsha Okiye, Brendan Kemple, Department of Internal Medicine, Medical College of Georgia, Augusta, GA 30912, United States

Author contributions: Hudgi A, Sifuentes H, and Sridhar S conceptualized the narrative review; Hudgi A, Woodcock A, Mirza A, Okiye P, and Kemple B performed the research and wrote portions of the article; Hudgi A and Woodcock A reviewed and edited the article.

AI contribution statement: The authors certify that this article was researched, written, and edited without generative AI software.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Corresponding author: Alexander Woodcock, Department of Internal Medicine, Medical College of Georgia, 1120 W 15^th Street, Augusta, GA 30912, United States. awoodcock@augusta.edu

Received: February 7, 2026
Revised: March 13, 2026
Accepted: May 7, 2026
Published online: August 21, 2026
Processing time: 178 Days and 18.3 Hours

Core Tip

Core Tip: Pancreatic cancer is a diagnosis that is often devastating due to high mortality rates. This review covers up-to-date data regarding global incidence and mortality, then further delves into important risk factors for developing pancreatic cancer in detail. Some of the risk factors discussed are modifiable, such as tobacco or alcohol use, while others are not modifiable, like age, race, or genetics. Finally, this review covers current screening and surveillance recommendations.