Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastroenterol. Aug 21, 2026; 32(31): 118374
Published online Aug 21, 2026. doi: 10.3748/wjg.118374
Published online Aug 21, 2026. doi: 10.3748/wjg.118374
From risk stratification to precision surveillance: Interpreting early-warning models after laparoscopic resection for hepatocellular carcinoma
Veena Shekar, Department of General Medicine, The Oxford Medical College Hospital and Research Centre, Bengaluru 562107, Karnataka, India
Brandon Lucke-Wold, Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville, FL 32608, United States
Author contributions: Shekar V contributed to conceptualization, manuscript drafting, and critical revision; Lucke-Wold B provided senior supervision, intellectual input, and final approval.
AI contribution statement: The manuscript was conceptualized, written, and critically revised by the authors. During the revision stage, limited AI-assisted tools were used to improve clarity, grammar, and overall readability of the manuscript. No AI tools were used to generate original scientific ideas, interpret results, or draw conclusions. No part of the scientific content, data interpretation, or analytical reasoning in this manuscript was generated or performed using AI tools. All interpretations are based on the authors’ independent academic assessment of the cited literature. The conceptual framework figure and tabulated summary were developed by the authors. AI-assisted tools were used only for formatting and improving visual presentation to meet journal standards. All references were selected by the authors following a structured literature review. AI tools were not used to independently generate references; however, they were occasionally used to assist in formatting and organizing citations.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Corresponding author: Brandon Lucke-Wold, MD, PhD, Doctor, Lillian S. Wells Department of Neurosurgery, University of Florida, 1505 SW Archer Road, Gainesville, FL 32608, United States. brandon.lucke-wold@neurosurgery.ufl.edu
Received: January 4, 2026
Revised: January 16, 2026
Accepted: April 15, 2026
Published online: August 21, 2026
Processing time: 216 Days and 19.3 Hours
Revised: January 16, 2026
Accepted: April 15, 2026
Published online: August 21, 2026
Processing time: 216 Days and 19.3 Hours
Core Tip
Core Tip: This opinion review discusses the clinical implications of a recently published early-warning model predicting one-year adverse outcomes after laparoscopic resection for hepatocellular carcinoma. The model integrates inflammatory markers, tumor burden, and hepatic reserve to support individualized postoperative surveillance and precision management.