Peltec A, Sporea I. Preventive strategies in hepatology: Role of multiparametric assessment of portal hypertension in chronic liver disease. World J Gastroenterol 2026; 32(29): 119106 [DOI: 10.3748/wjg.119106]
Corresponding Author of This Article
Angela Peltec, MD, PhD, Associate Professor, Discipline of Gastroenterology, Department of Internal Medicine, “Nicolae Testemitanu” State University of Medicine and Pharmacy, Str. Testemitanu 29, Chishinev 2019, Moldova. angela.peltec@usmf.md
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
review-article
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Peltec A, Sporea I. Preventive strategies in hepatology: Role of multiparametric assessment of portal hypertension in chronic liver disease. World J Gastroenterol 2026; 32(29): 119106 [DOI: 10.3748/wjg.119106]
World J Gastroenterol. Aug 7, 2026; 32(29): 119106 Published online Aug 7, 2026. doi: 10.3748/wjg.119106
Preventive strategies in hepatology: Role of multiparametric assessment of portal hypertension in chronic liver disease
Angela Peltec, Ioan Sporea
Angela Peltec, Discipline of Gastroenterology, Department of Internal Medicine, “Nicolae Testemitanu” State University of Medicine and Pharmacy, Chishinev 2019, Moldova
Ioan Sporea, Department of Gastroenterology and Hepatology, “Victor Babes” University of Medicine and Pharmacy, Timisoara 300736, Romania
Author contributions: Peltec A contributed to the conception of the review and writing of the manuscript; Sporea I provided important intellectual contributions to the study and various revisions of the manuscript; and all authors read and approved the final version of the manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Corresponding author: Angela Peltec, MD, PhD, Associate Professor, Discipline of Gastroenterology, Department of Internal Medicine, “Nicolae Testemitanu” State University of Medicine and Pharmacy, Str. Testemitanu 29, Chishinev 2019, Moldova. angela.peltec@usmf.md
Received: January 19, 2026 Revised: February 9, 2026 Accepted: April 8, 2026 Published online: August 7, 2026 Processing time: 179 Days and 12.2 Hours
Core Tip
Core Tip: The goal of preventive hepatology is to reduce the burden of liver disease through early detection, risk stratification, and timely intervention. Assessing portal hypertension in patients with advanced chronic liver disease is essential for predicting decompensation and guiding clinical management. Noninvasive imaging techniques, particularly multiparametric ultrasound (MPUS), are valuable approaches for evaluating portal hemodynamics. Combining Doppler ultrasound, contrast-enhanced ultrasound, elastography, and endoscopic ultrasound, MPUS enables accurate, accessible, and radiation-free assessment of liver disease severity. The integration of MPUS into routine care will support effective screening and monitoring to ultimately improve outcomes.
