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World J Gastroenterol. Jul 28, 2026; 32(28): 119134
Published online Jul 28, 2026. doi: 10.3748/wjg.119134
Published online Jul 28, 2026. doi: 10.3748/wjg.119134
Timeliness-incentive home health management for metabolic dysfunction-associated steatotic liver disease
Jia Mei, Yu-Di Jin, Yun-Cai Xie, Ping-Ping Huang, Yu Deng, Ying Chen, Health Medicine Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
Author contributions: Mei J contributed to analysis and interpretation of data, drafting of the manuscript, statistical analysis, and study design; Chen Y contributed to study concept, study supervision, critical revision of the manuscript for important intellectual content; Jin YD, Xie YC, and Huang PP contributed to study design, acquisition of data; Deng Y contributed to acquisition of data.
Institutional review board statement: The study was approved by the Clinical Research Ethics Committee of the Second Affiliated Hospital of Chongqing Medical University, No. 2024-55.
Clinical trial registration statement: The study registered at the Chinese Clinical Trial Registry. The registration identification number is ChiCTR2500096119.
Informed consent statement: Written informed consent was obtained from each patient included in the study.
Conflict-of-interest statement: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: The participant data is solely for this research and will not be made public. If the editor requires it, the original data can be provided via email.
Corresponding author: Ying Chen, Chief Nurse, Principal Investigator, Professor, Health Medicine Center, The Second Affiliated Hospital of Chongqing Medical University, No. 74 Linjiang Road, Yuzhong District, Chongqing 400010, China. 300492@hospital.cqmu.edu.cn
Received: January 20, 2026
Revised: February 8, 2026
Accepted: April 7, 2026
Published online: July 28, 2026
Processing time: 173 Days and 21 Hours
Revised: February 8, 2026
Accepted: April 7, 2026
Published online: July 28, 2026
Processing time: 173 Days and 21 Hours
Core Tip
Core Tip: In a home-based "timeliness-incentive" randomized clinical trial, 108 metabolic dysfunction-associated steatotic liver disease patients receiving home care plus micro, immediate rewards for 7 months showed markedly lower liver fat, weight, aspartate aminotransferase/alanine aminotransferase, lipids and higher high-density lipoprotein cholesterol vs usual care, alongside superior diet, exercise and self-management scores, proving that low-cost timeliness-incentive tele-health can reverse metabolic-liver injury and should be widely adopted.