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World J Gastroenterol. Jul 14, 2026; 32(26): 118889
Published online Jul 14, 2026. doi: 10.3748/wjg.118889
Published online Jul 14, 2026. doi: 10.3748/wjg.118889
Balloon-assisted endoscopic stricturotomy for small bowel fibrostenotic strictures: A comparison of Crohn’s disease-related and non-Crohn’s disease strictures
Wen-Cai Lai, Zhi-Meng Jiang, Graduate School, Hebei North University, Zhangjiakou 075031, Hebei Province, China
Wen-Cai Lai, Xiao-Meng Feng, Zhi-Han Huang, Zhi-Meng Jiang, Tao Sun, Xin Yin, Lei Zhang, Shou-Bin Ning, Bai-Rong Li, Department of Gastroenterology, Air Force Medical Center, Air Force Medical University, Beijing 100142, China
Co-first authors: Wen-Cai Lai and Xiao-Meng Feng.
Co-corresponding authors: Shou-Bin Ning and Bai-Rong Li.
Author contributions: Ning SB and Li BR designed the research study and critically revised the manuscript for important intellectual content and they contribute equally to this study as co-corresponding authors; Lai WC and Feng XM analyzed the data and drafted the manuscript and they contribute equally to this study as co-first authors; Lai WC, Feng XM, Huang ZH, and Jiang ZM collected the data; Li BR, Sun T, Yin X, and Zhang L performed the endoscopic stricturotomy procedures; all authors approved the final version of the manuscript and agree to be accountable for all aspects of the work.
Supported by the Capital Health Research and Development Special Fund, No. 2020-4-5123.
Institutional review board statement: This study was approved by the Ethics Committee of the Air Force Medical Center, Air Force Medical University (Approval No. 2022-170-PJ01).
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: The datasets used and/or analyzed during the current study are not publicly available due to institutional regulations on patient privacy but are available from the corresponding author upon reasonable request.
Corresponding author: Bai-Rong Li, MD, PhD, Department of Gastroenterology, Air Force Medical Center, Air Force Medical University, No. 30 Fuchen Road, Beijing 100142, China.
Received: January 16, 2026
Revised: February 17, 2026
Accepted: March 9, 2026
Published online: July 14, 2026
Processing time: 162 Days and 21.5 Hours
Revised: February 17, 2026
Accepted: March 9, 2026
Published online: July 14, 2026
Processing time: 162 Days and 21.5 Hours
Core Tip
Core Tip: Endoscopic stricturotomy is an established minimally invasive treatment for small-bowel fibrostenotic strictures, but whether outcomes differ by stricture etiology is not well defined. In this retrospective study with long-term follow-up, non-Crohn’s disease strictures had more durable reintervention-free survival than Crohn’s disease-related strictures. A lower neutrophil-to-lymphocyte ratio was associated with a lower risk of reintervention, supporting its use as a simple preprocedural risk marker.