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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 14, 2026; 32(2): 115178
Published online Jan 14, 2026. doi: 10.3748/wjg.v32.i2.115178
Published online Jan 14, 2026. doi: 10.3748/wjg.v32.i2.115178
The triglyceride-glucose index shows promise as a novel prognostic marker for advanced hepatocellular carcinoma
Tao Xu, Nian-Song Qian, Department of Thoracic Oncology, Respiratory and Critical Care Medicine, The Eighth Medical Center of People’s Liberation Army General Hospital, Beijing 100091, China
Xu Qi, Department of Radiology, Peking Union Medical College Hospital, Beijing 100730, China
Fei-Yu Zhao, Department of Radiation Oncology, The Fifth Medical Center of Chinese People’s Liberation Army General Hospital, Beijing 100071, China
Co-first authors: Tao Xu and Xu Qi.
Co-corresponding authors: Fei-Yu Zhao and Nian-Song Qian.
Author contributions: Xu T and Qi X wrote and revised the manuscript; Zhao FY and Qian NS gave notes and suggestions.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fei-Yu Zhao, PhD, Doctor, Department of Radiation Oncology, The Fifth Medical Center of Chinese People’s Liberation Army General Hospital, No. 8 East Main Street, Fengtai District, Beijing 100071, China. 1029279130@qq.com
Received: October 10, 2025
Revised: November 16, 2025
Accepted: December 23, 2025
Published online: January 14, 2026
Processing time: 94 Days and 15.9 Hours
Revised: November 16, 2025
Accepted: December 23, 2025
Published online: January 14, 2026
Processing time: 94 Days and 15.9 Hours
Core Tip
Core Tip: This commentary highlights triglyceride-glucose (TyG) index as a prognostic marker for hepatitis B virus-related advanced hepatocellular carcinoma on camrelizumab-lenvatinib. Low TyG (< 1.58) boosts survival, it’s an independent predictor, with limitations needing multicenter studies.