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World J Gastroenterol. May 21, 2026; 32(19): 117166
Published online May 21, 2026. doi: 10.3748/wjg.v32.i19.117166
Published online May 21, 2026. doi: 10.3748/wjg.v32.i19.117166
Presentation and treatment of eosinophilic gastroenteritis in Busan and Gyeongnam, Korea: A multicenter study
Jin Lee, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan 48108, South Korea
Sung Eun Kim, Department of Internal Medicine, Kosin University College of Medicine, Busan 49267, South Korea
Ra Ri Cha, Department of Internal Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Changwon Hospital, Changwon 51472, South Korea
Bong Eun Lee, Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 47241, South Korea
Cheol Woong Choi, Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, South Korea
Sam Ryong Jee, Department of Internal Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan 47392, South Korea
Co-first authors: Jin Lee and Sung Eun Kim.
Author contributions: Lee J and Kim SE contributed to this work and were responsible for study design, data collection, and manuscript drafting, they contributed equally to this article, they are the co-first authors of this manuscript; Cha RR, Lee BE, and Choi CW contributed to data interpretation and manuscript revision; Jee SR supervised the study and approved the final version; and all authors thoroughly reviewed and endorsed the final manuscript.
Supported by the Korean College of Helicobacter and Upper Gastrointestinal Research Foundation Grant, No. KCHUGR-202302503; and Research Year of Inje University in 2024, No. 20240024.
Institutional review board statement: The study protocol was approved by the Institutional Review Boards of all the participating centers. The leading institution was Inje University Haeundae Paik Hospital (approval number: HPIRB 2024-01-026).
Informed consent statement: The requirement for written informed consent was waived by the Institutional Review Boards of all participating centers because this retrospective study used anonymized medical records.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data underlying this study are available from the corresponding author upon reasonable request.
Corresponding author: Sam Ryong Jee, MD, PhD, Professor, Department of Internal Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine, 75 Bokji-ro, Busanjin-gu, Busan 47392, South Korea. tokimom@nate.com
Received: December 2, 2025
Revised: February 9, 2026
Accepted: February 26, 2026
Published online: May 21, 2026
Processing time: 168 Days and 10.4 Hours
Revised: February 9, 2026
Accepted: February 26, 2026
Published online: May 21, 2026
Processing time: 168 Days and 10.4 Hours
Core Tip
Core Tip: This retrospective multicenter cohort study analyzed 73 Korean patients with eosinophilic gastroenteritis. The clinical features, endoscopic findings, treatment modalities, and outcomes were evaluated based on the disease location. Corticosteroids and proton pump inhibitors were the main treatments with high clinical response rates. Relapse was more frequent in patients with colonic involvement, and male sex was suggested to be associated with a favorable treatment response. These findings provide real-world insights into eosinophilic gastroenteritis management in Korea, emphasizing the need for tailored therapies and close follow-up in high-risk groups.