©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 7, 2025; 31(5): 97574
Published online Feb 7, 2025. doi: 10.3748/wjg.v31.i5.97574
Published online Feb 7, 2025. doi: 10.3748/wjg.v31.i5.97574
Advances and challenges in peroral endoscopic myotomy: Safety, precision, and post-procedure management
Grigorios Christodoulidis, Marina Nektaria Kouliou, Department of General Surgery, University Hospital of Larissa, Larissa 41110, Greece
Kyriaki Tsagkidou, Department of Gastroenterology, General Hospital of Larissa, Larisa 41221, Thessalía, Greece
Konstantinos Eleftherios Koumarelas, Department of Emergency Medicine, General Hospital of Larissa, Larissa 41221, Greece
Author contributions: Christodoulidis G designed the overall concept and outline of the manuscript; Christodoulidis G, Tsagkidou K, Koumarelas KE and Kouliou MN contributed to the discussion, manuscript design, the writing, editing the manuscript, and review of literature; All authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: The authors declare no conflict of interest in publishing the manuscript.
Corresponding author: Grigorios Christodoulidis, PhD, Executive Associate Editor-in-Chief, Department of General Surgery, University Hospital of Larissa, Mezourlo, Larissa 41110, Greece. gregsurg@yahoo.gr
Received: June 2, 2024
Revised: November 12, 2024
Accepted: December 4, 2024
Published online: February 7, 2025
Processing time: 210 Days and 13.9 Hours
Revised: November 12, 2024
Accepted: December 4, 2024
Published online: February 7, 2025
Processing time: 210 Days and 13.9 Hours
Core Tip
Core Tip: Peroral endoscopic myotomy (POEM) has emerged as a transformative treatment for upper gastrointestinal motility disorders, offering significant long-term efficacy with minimal adverse events. Keys to its success include precision in myotomy techniques, interdisciplinary collaboration for enhanced safety, and ongoing efforts to standardize protocols and manage complications. As POEM techniques advance and applications broaden, they promise to revolutionize the manage