Ascites in acute pancreatitis: A window into disease severity

doi:10.3748/wjg.v31.i43.112797

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Nov 21, 2025 (publication date) through Nov 20, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2025; 31(43): 112797
Published online Nov 21, 2025. doi: 10.3748/wjg.v31.i43.112797

Ascites in acute pancreatitis: A window into disease severity

Enver Zerem, Dina Zerem, Šeila Vila, Sanja Bajgorić

Enver Zerem, Department of Medical Sciences, The Academy of Sciences and Arts of Bosnia and Herzegovina, Sarajevo 71000, Bosnia and Herzegovina

Dina Zerem, Šeila Vila, Sanja Bajgorić, Department of Health Studies, University Dzemal Bijedić Mostar, Mostar 88000, Bosnia and Herzegovina

Co-first authors: Enver Zerem and Dina Zerem.

Author contributions: Zerem E contributed to the conception and design of the paper, writing of the paper, and final revision; Vila Š, Bajgorić S and Zerem D contributed to the literature search, writing of the paper, and final revision of the paper.

Conflict-of-interest statement: The authors declare that they have no conflicts of interest.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Enver Zerem, MD, Full Professor, Department of Medical Sciences, The Academy of Sciences and Arts of Bosnia and Herzegovina, Bistrik 7, Sarajevo 71000, Bosnia and Herzegovina. zerem@anubih.ba

Received: August 6, 2025
Revised: September 14, 2025
Accepted: October 17, 2025
Published online: November 21, 2025
Processing time: 106 Days and 9.5 Hours

Core Tip

Core Tip: There is increasing evidence that ascites in acute pancreatitis is more than an epiphenomenon. It reflects disease severity, provides actionable clinical information on inflammatory burden, vascular permeability, and risk of complications, and may serve as a target for personalized therapeutic strategies. Its biochemical and cellular composition can further support early risk stratification and guide treatment decisions.