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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 14, 2025; 31(38): 110557
Published online Oct 14, 2025. doi: 10.3748/wjg.v31.i38.110557
Published online Oct 14, 2025. doi: 10.3748/wjg.v31.i38.110557
Clinical features of early esophageal neoplastic lesions at different stages and efficacy and prognosis after endoscopic submucosal dissection
Yuan-Miao Zhang, Ning Zhu, Meng-Yao Chen, Bin Qin, Jiong Jiang, Shen-Hao Wang, Xiao-Jing Quan, Chu-Ying Wang, Ying Zheng, Bai-Cang Zou, Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, China
Fang-Lan Li, Department of Gastroenterology, Xianyang Hospital of Yan'an University, Xianyang 712000, Shaanxi Province, China
Jie Wu, Department of Pathology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, China
Co-first authors: Yuan-Miao Zhang and Ning Zhu.
Author contributions: Zhang YM and Zhu N drafted the manuscript; Chen MY collected and analyzed data; Li FL, Qin B, Jiang J, Wang SH, Wu J, Quan XJ, Wang CY, and Zheng Y contributed to data analysis and interpretation; Zou BC designed the study and critically revised the manuscript. All authors approved the final version.
Supported by the Development Program of Shaanxi Province, No. 2021SF-221.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of The Second Affiliated Hospital of Xi'an Jiaotong University, No. 2024 Ethics Review 032.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors no conflicts of interest to declare.
Data sharing statement: The data that support the findings of this study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bai-Cang Zou, PhD, Chief Physician, Professor, Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 West Fifth Road, Xi'an 710004, Shaanxi Province, China. zoubaicang2@163.com
Received: June 11, 2025
Revised: July 14, 2025
Accepted: September 1, 2025
Published online: October 14, 2025
Processing time: 127 Days and 15.7 Hours
Revised: July 14, 2025
Accepted: September 1, 2025
Published online: October 14, 2025
Processing time: 127 Days and 15.7 Hours
Core Tip
Core Tip: This study examined 264 cases of esophageal mucosal lesions in 245 patients who underwent endoscopic submucosal dissection (ESD) treatment. The study found that esophageal tumors with different levels of differentiation exhibit differences in clinical and pathological characteristics. While ESD demonstrated sustained efficacy, elderly patients and those with a history of esophageal cancer had poorer prognoses and required close follow-up.