Editorial
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 21, 2025; 31(3): 100393
Published online Jan 21, 2025. doi: 10.3748/wjg.v31.i3.100393
Red cell distribution width/platelet ratio predicts decompensation of metabolic dysfunction-associated steatotic liver disease-related compensated advanced chronic liver disease
Ming-Hua Zheng, Amedeo Lonardo
Ming-Hua Zheng, Department of Hepatology, MAFLD Research Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Amedeo Lonardo, Department of Internal Medicine, Azienda Ospedaliero-Universitaria of Modena (2023), Modena 41126, Italy
Author contributions: Both authors equally contributed to the conception of the study, and manuscript preparation and revision; both authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: There is no conflict of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming-Hua Zheng, PhD, Doctor, Professor, Teacher, Department of Hepatology, MAFLD Research Center, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, Ouhai District, Wenzhou 325000, Zhejiang Province, China. zhengmh@wmu.edu.cn
Received: August 15, 2024
Revised: November 12, 2024
Accepted: December 2, 2024
Published online: January 21, 2025
Processing time: 127 Days and 2 Hours
Core Tip

Core Tip: A recent paper published in World Journal of Gastroenterology reports on the utility of red cell distribution width (RDW)/platelet ratio, a non-expensive and universally available biomarker based on RDW and platelet count, in predicting decompensation of metabolic dysfunction-associated steatotic liver disease (MASLD)-related compensated advanced chronic liver disease (cACLD) (MASLD-cACLD). We discuss these novel findings in the context of MASLD natural history and of a foreseeable research agenda pertaining to the stratification of MASLD-cACLD.