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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 28, 2025; 31(28): 109078
Published online Jul 28, 2025. doi: 10.3748/wjg.v31.i28.109078
Published online Jul 28, 2025. doi: 10.3748/wjg.v31.i28.109078
Efficacy and safety of transcatheter arterial chemoembolization combined with microwave ablation for hepatic hemangiomas (> 5 cm)
Jia-Peng Sun, Kang Zhou, Jie Pan, Ning Yang, Xiao-Nan Sun, Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
Hai-Tao Zhao, Xiao-Bo Yang, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Co-first authors: Jia-Peng Sun and Kang Zhou.
Author contributions: Sun JP, Zhou K, Pan J, Yang N, and Sun XN designed the research study; Sun JP and Zhou K contributed equally to this article, they are the co-first authors of this manuscript; Sun JP, Zhou K, Yang N, and Sun XN performed the research and acquired the data; Zhao HT and Yang XB contributed to the multidisciplinary evaluation of patients; Sun JP and Zhou K analyzed the data; Sun JP, Zhou K, Pan J, Zhao HT, and Yang XB wrote and critically revised the manuscript; and all authors have read and approve the final manuscript.
Supported by the Peking Union Medical College Hospital Central High-Level Hospital Clinical Research Project, No. 2022-PUMCH-B-069.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Peking Union Medical College Hospital, approval No. 1-24PJ1959.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Participants gave informed consent for data sharing. Dataset available from the corresponding author at markpan6885@sina.com.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Pan, MD, Chief, Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. markpan6885@sina.com
Received: April 29, 2025
Revised: May 24, 2025
Accepted: July 4, 2025
Published online: July 28, 2025
Processing time: 86 Days and 17.9 Hours
Revised: May 24, 2025
Accepted: July 4, 2025
Published online: July 28, 2025
Processing time: 86 Days and 17.9 Hours
Core Tip
Core Tip: This study compares two treatment options for large liver hemangiomas, a type of benign tumor. We found that combining transcatheter arterial chemoembolization and microwave ablation was more effective at shrinking tumors and preventing recurrence compared to transcatheter arterial chemoembolization alone. Patients with large liver hemangiomas experienced fewer complications on the combined treatment which may be a safer alternative to surgery.