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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Multiparametric ultrasound for non-invasive assessment of liver steatosis, fibrosis, and inflammation in metabolic dysfunction-associated steatotic liver disease
Antonio Liguori, Maria E Ainora, Luca Di Gialleonardo, Nicholas Viceconti, Lucrezia Petrucci, Giorgio Esposto, Maria C Giustiniani, Irene Mignini, Raffaele Borriello, Linda Galasso, Mattia Paratore, Matteo Garcovich, Laura Riccardi, Maurizio Pompili, Antonio Grieco, Antonio Gasbarrini, Luca Miele, Maria A Zocco
Antonio Liguori, Nicholas Viceconti, Lucrezia Petrucci, Maurizio Pompili, Antonio Grieco, Luca Miele, Unità di Medicina Interna e Trapianto di Fegato, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome 00168, Italy
Maria E Ainora, Luca Di Gialleonardo, Giorgio Esposto, Irene Mignini, Raffaele Borriello, Linda Galasso, Mattia Paratore, Matteo Garcovich, Laura Riccardi, Antonio Gasbarrini, Maria A Zocco, CEMAD, Centro Malattie Apparato Digerente, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome 00168, Italy
Maria C Giustiniani, Dipartimento di Scienze Della Salute Della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome 00168, Italy
Author contributions: Zocco MA and Miele L contributed to conceptualization; Liguori A, Ainora ME, Miele L, and Zocco MA contributed to methodology; Liguori A contributed to formal analysis; Liguori A, Ainora ME, Di Gialleonardo L, Petrucci L, Viceconti N, Mignini I, Borriello R, Galasso L, Garcovich M, Giustiniani MC, and Paratore M contributed to the investigation; Liguori A, Di Gialleonardo L, Viceconti N, and Petrucci L contributed to data curation; Liguori A and Ainora ME contributed to writing the original draft; Liguori A, Ainora ME, Esposto G, Miele L, and Zocco MA contributed to writing and reviewing; Liguori A, Ainora ME, Esposto G, Miele L, and Zocco MA contributed to editing; Miele L, Pompili M, Zocco MA, Grieco A, Riccardi L, and Gasbarrini A contributed to supervision; Gasbarrini A, Miele L, and Zocco MA contributed to funding acquisition; All authors read and approved the final version of the manuscript.
Institutional review board statement: Protocol was approved by local ethic committee [Prot. 20048/19 (28519/19) ID: 2576].
Clinical trial registration statement: Protocol was registered on clinical trial (No. NCT04371042).
Informed consent statement: Written informed consent was obtained by every patient.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: All article data are available in the paper.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Maria A Zocco, MD, PhD, Professor, CEMAD, Centro Malattie Apparato Digerente, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Gemelli 1, Rome 00168, Italy.
mariaassunta.zocco@unicatt.it
Received: February 7, 2025
Revised: March 27, 2025
Accepted: June 10, 2025
Published online: July 7, 2025
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