Prediction, prevention and management of gastroesophageal reflux after per-oral endoscopic myotomy: An update

Core Tip

Core Tip: Per-oral endoscopic myotomy (POEM) has gained recognition as a primary therapeutic intervention for achalasia cardia. POEM is distinguished by its effectiveness and a commendable safety profile. However, gastroesophageal reflux disease (GERD) has emerged as an important long term adverse event after POEM. Notably, the incidence of GERD is higher after POEM when compared to the other leading treatment modalities including pneumatic dilatation and Heller’s myotomy with fundoplication. Since the introduction of POEM in 2010, there has been considerable advancement in our understanding of GERD after POEM. This article aims to elucidate the recent developments in predicting, preventing, assessing, and managing GERD subsequent to POEM intervention.