Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 21, 2024; 30(47): 5076-5080
Published online Dec 21, 2024. doi: 10.3748/wjg.v30.i47.5076
Roles of traditional Chinese medicine extracts in hyperuricemia and gout treatment: Mechanisms and clinical applications
Yan-Bo Wang, Chang-Zhong Jin
Yan-Bo Wang, Chang-Zhong Jin, Department of Cell Biology, Jinan Microecological Biomedicine Shandong Laboratory, Jinan 250117, Shandong Province, China
Chang-Zhong Jin, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Wang YB and Jin CZ designed the overall concept and contributed to writing, editing and review of the literature.
Supported by Zhejiang Province Leading Geese Program, No. 2024C03218; and Research Project of Jinan Microecological Biomedicine Shandong Laboratory, No. JNL-2023010Q.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chang-Zhong Jin, PhD, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. changzhongjin@163.com
Received: July 31, 2024
Revised: October 23, 2024
Accepted: November 7, 2024
Published online: December 21, 2024
Processing time: 118 Days and 0.3 Hours
Core Tip

Core Tip: Traditional Chinese medicines (TCMs) have significant potential in treating hyperuricemia (HUA), gout and other metabolic diseases. However, the “multi-target effects” do not fully explain the mechanisms of TCMs, hindering their clinical application. The active components and mechanisms of TCMs should be elucidated in detail. Additionally, the side effects of TCMs need attention. The role of gut microbiota in treating HUA also warrants further investigation to improve HUA and gout treatment strategies.