Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 21, 2024; 30(47): 5007-5017
Published online Dec 21, 2024. doi: 10.3748/wjg.v30.i47.5007
Comprehensive analysis of risk factors associated with submucosal invasion in patients with early-stage gastric cancer
Bin-Bin Yan, Li-Na Cheng, Hui Yang, Xiu-Ling Li, Xiu-Qi Wang
Bin-Bin Yan, Li-Na Cheng, Hui Yang, Xiu-Ling Li, Xiu-Qi Wang, Department of Gastroenterology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou 450000, Henan Province, China
Author contributions: Yan BB conceptualized the study and played a central role in literature search, data extraction, quality assessment, data analysis, and manuscript preparation; Cheng LN also made important contributions; Yan BB, Yang H, and Li XL worked on refining the language, style, and protocol of the article; Yan BB further contributed to the analysis through constructive discussions; Wang XQ revised the manuscript and approved the final version for submission.
Institutional review board statement: This study was approved by the Henan Provincial People's Hospital, Zhengzhou University People's Hospital (H-2023173).
Informed consent statement: Informed consent for publication was obtained from all patients and/or their families included in this retrospective analysis.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: The data sets generated and analyzed during this study are not public, but under reasonable requirements, the correspondence author can provide.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiu-Qi Wang, MM, Doctor, Department of Gastroenterology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, No. 7 Weiwu Road, Jinshui District, Zhengzhou 450000, Henan Province, China. xiuqiwang00123@163.com
Received: September 5, 2024
Revised: October 25, 2024
Accepted: October 31, 2024
Published online: December 21, 2024
Processing time: 81 Days and 16.4 Hours
Core Tip

Core Tip: Our research provides an in-depth analysis of multiple risk factors that influence submucosal invasion in early-stage gastric cancer, which is pivotal for determining prognosis and tailoring treatment strategies. This retrospective study, conducted over four years at our institution, integrates a broad spectrum of data points-including clinical, imaging, and endoscopic characteristics-to identify significant predictors of submucosal invasion. Our findings underscore the importance of specific endoscopic features and demographic factors in predicting the depth of tumor invasion, thereby aiding in the clinical decision-making process.