©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 28, 2024; 30(40): 4380-4385
Published online Oct 28, 2024. doi: 10.3748/wjg.v30.i40.4380
Published online Oct 28, 2024. doi: 10.3748/wjg.v30.i40.4380
Promise and challenges of traditional Chinese medicine, specifically Calculus bovis, in liver cancer treatment
Ao-Xi Xu, Yu-Fan Wei, Bo-Ya Zhang, Bin Jiang, Tian-Ze Gao, School of Medicine, Nankai University, Tianjin 300071, China
Ao-Xi Xu, Li Zhu, Yi-Heng Zhang, Yan Li, Department of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing 100853, China
Ao-Xi Xu, Zhi-Feng Zhao, Yi-Heng Zhang, Medical School of Chinese People's Liberation Army, Medical School of Chinese People's Liberation Army, Beijing 100853, China
Zhi-Feng Zhao, Department of Hepatobiliary and Pancreative Surgery, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China
Meng-Si Li, Department of Surgery, Mancheng District People's Hospital, Baoding 072150, Hebei Province, China
Jia-Yu Liu, Department of Neurosurgery, First Medical Centre of Chinese People's Liberation Army General Hospital, Beijing 100853, China
Author contributions: Xu AX, Liu JY and Zhao ZF conceived and designed the topic of the article; Zhu L, Zhang YH, Li Y, Wei YF, Zhang BY, Jiang B, Gao TZ and Li MS collected relative data and materials; Xu AX and Zhao ZF contributed to drafting of the article; Liu JY contributed to critical revision of the article for important intellectual content and final approval of the article.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Corresponding author: Jia-Yu Liu, MD, PhD, Attending Doctor, Department of Neurosurgery, First Medical Centre of Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. liujiayu@pku.edu.cn
Received: July 17, 2024
Revised: September 16, 2024
Accepted: September 26, 2024
Published online: October 28, 2024
Processing time: 90 Days and 14.1 Hours
Revised: September 16, 2024
Accepted: September 26, 2024
Published online: October 28, 2024
Processing time: 90 Days and 14.1 Hours
Core Tip
Core Tip: Huang et al discovered that Calculus bovis (CB) inhibits liver cancer growth by mediating the suppression of M2-TAM polarization through the Wnt/β-catenin pathway. This article highlights the current research, potential, and challenges of using traditional Chinese medicine, exemplified by CB, in liver cancer treatment, and points to future research directions.