Zhao WZ, Wang HG, Yang XZ. Leukocyte immunoglobulin-like receptor B2: A promising biomarker for colorectal cancer. World J Gastroenterol 2024; 30(4): 421-423 [PMID: 38313233 DOI: 10.3748/wjg.v30.i4.421]
Corresponding Author of This Article
Xiao-Zhong Yang, MD, PhD, Chief Doctor, Doctor, Professor, Department of Gastroenterology, The Affiliated Huaian No. 1 People’s Hospital of Nanjing Medical University, No. 1 Huanghe Road, Huai’an 223300, Jiangsu Province, China. hayyyxzh@njmu.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jan 28, 2024; 30(4): 421-423 Published online Jan 28, 2024. doi: 10.3748/wjg.v30.i4.421
Leukocyte immunoglobulin-like receptor B2: A promising biomarker for colorectal cancer
Wen-Zhuo Zhao, Hong-Gang Wang, Xiao-Zhong Yang
Wen-Zhuo Zhao, Hong-Gang Wang, Xiao-Zhong Yang, Department of Gastroenterology, The Affiliated Huai'an No. 1 People's Hospital of Nanjing Medical University, Huai'an 223300, Jiangsu Province, China
Author contributions: Zhao WZ wrote the letter; Wang HG revised the letter; and Yang XZ contributed to the study design, manuscript revision, supervision of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Xiao-Zhong Yang, MD, PhD, Chief Doctor, Doctor, Professor, Department of Gastroenterology, The Affiliated Huaian No. 1 People’s Hospital of Nanjing Medical University, No. 1 Huanghe Road, Huai’an 223300, Jiangsu Province, China. hayyyxzh@njmu.edu.cn
Received: October 17, 2023 Peer-review started: October 17, 2023 First decision: December 6, 2023 Revised: December 15, 2023 Accepted: January 10, 2024 Article in press: January 10, 2024 Published online: January 28, 2024 Processing time: 101 Days and 4.2 Hours
Core Tip
Core Tip: In this study, it has been extensively demonstrated that there is an overexpression of leukocyte immunoglobulin-like receptor B2 (LILRB2) and its ligand angiopoietin-like protein 2 in colorectal cancer tissues. Furthermore, these proteins have been found to be closely associated with tumor progression and poor prognosis. The author conducted an analysis of LILRB2 serum concentration using 313 serum samples and compared its advantages and disadvantages with traditional tumor markers such as carcinoembryonic antigen and carbohydrate antigen 199. However, we believe that certain aspects of data collection and analysis in the article warrant further consideration. Therefore, we would like to discuss our perspective on this intriguing research.
