Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 28, 2024; 30(36): 4071-4077
Published online Sep 28, 2024. doi: 10.3748/wjg.v30.i36.4071
Liver transplantation following two conversions in a patient with huge hepatocellular carcinoma and portal vein invasion: A case report
Li-Cong Liang, Wen-Sou Huang, Zhao-Xiong Guo, Hong-Ji You, Yong-Jian Guo, Ming-Yue Cai, Li-Teng Lin, Guo-Ying Wang, Kang-Shun Zhu
Li-Cong Liang, Wen-Sou Huang, Zhao-Xiong Guo, Yong-Jian Guo, Ming-Yue Cai, Li-Teng Lin, Kang-Shun Zhu, Department of Minimally Invasive Interventional Radiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, Guangdong Province, China
Hong-Ji You, Department of Nuclear Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, Guangdong Province, China
Guo-Ying Wang, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
Author contributions: Zhu KS guided the treatment plan; Huang WS, Guo YJ, Cai MY and Wang GY performed the interventional procedures and transplant surgery respectively; Guo ZX and You HJ collected and edited figures; Liang LC, Lin LT and Zhu KS analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Informed consent statement: Informed Written consent was obtained from the patient. This case was approved by the Institutional Review Board of the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China (No. 2024-hg-ks-04).
Conflict-of-interest statement: All the authors have no relevant conflicts of interest to declare for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kang-Shun Zhu, MD, PhD, Director, Doctor, Professor, Department of Minimally Invasive Interventional Radiology, The Second Affiliated Hospital of Guangzhou Medical University, No. 250 East Changgang Road, Guangzhou 510260, Guangdong Province, China. zhksh010@163.com
Received: March 2, 2024
Revised: August 23, 2024
Accepted: September 3, 2024
Published online: September 28, 2024
Processing time: 201 Days and 18.8 Hours
Core Tip

Core Tip: We report a patient with > 20 cm hepatocellular carcinoma (HCC) and portal vein tumor thrombus (PVTT) who successfully received liver transplantation (LT) after two conversions. He was first converted to selective internal radiation therapy (SIRT) eligibility with transarterial chemoembolization and infusion chemotherapy combined with systemic therapy and then converted to LT with SIRT and continued systemic therapy. This is significant because few patients with huge (> 10 cm in diameter) HCC and PVTT can receive curative treatments or curative treatments after one conversion.