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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 21, 2024; 30(35): 3985-3995
Published online Sep 21, 2024. doi: 10.3748/wjg.v30.i35.3985
Published online Sep 21, 2024. doi: 10.3748/wjg.v30.i35.3985
Correlation between the neuroendocrine axis, microbial species, inflammatory response, and gastrointestinal symptoms in irritable bowel syndrome
Xin Zhang, Department of Gastroenterology, Tongde Hospital of Zhejiang Province, Taizhou 524333, Zhejiang Province, China
Wei-Wei Jin, Department of Nutrition, Tongde Hospital of Zhejiang Province, Taizhou 524333, Zhejiang Province, China
Hong-Gang Wang, Department of Gastroenterology, Taizhou Municipal Hospital, Taizhou 524333, Zhejiang Province, China
Author contributions: Zhang X conceptualized and designed the study, conducted the primary research, and contributed to the manuscript's writing and editing; Jin WW was responsible for data collection and analysis, result interpretation, and assisted in drafting the manuscript; Wang HG provided critical revisions, supervised the research process, and ensured the integrity and accuracy of the data.
Institutional review board statement: All procedures of this study were reviewed and approved by the Ethics Committee of the Taizhou Municipal Hospital.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: Not available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Gang Wang, PhD, Chief Physician, Department of Gastro
Received: June 28, 2024
Revised: August 22, 2024
Accepted: September 2, 2024
Published online: September 21, 2024
Processing time: 76 Days and 20.9 Hours
Revised: August 22, 2024
Accepted: September 2, 2024
Published online: September 21, 2024
Processing time: 76 Days and 20.9 Hours
Core Tip
Core Tip: The findings suggest that targeting the neuroendocrine axis, gut microbiome, and inflammatory pathways may offer novel therapeutic strategies to alleviate symptoms and improve the quality of life in irritable bowel syndrome patients.