©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2024; 30(12): 1651-1654
Published online Mar 28, 2024. doi: 10.3748/wjg.v30.i12.1651
Published online Mar 28, 2024. doi: 10.3748/wjg.v30.i12.1651
Pediatric stricturing Crohn's disease
Alessandro Boscarelli, Department of Pediatric Surgery and Urology, Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, Trieste 34137, Italy
Matteo Bramuzzo, Department of Gastrointestinal Endoscopy and Nutrition, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste 34137, Italy
Author contributions: Boscarelli A wrote the first draft of the manuscript; Boscarelli A and Bramuzzo M reviewed and revised the final manuscript. All authors listed on the manuscript have seen and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Alessandro Boscarelli, MD, Surgeon, Department of Pediatric Surgery and Urology, Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, Via dell'Istria, 65/1, Trieste 34137, Italy. alessandro.boscarelli@burlo.trieste.it
Received: December 25, 2023
Peer-review started: December 25, 2023
First decision: January 27, 2024
Revised: January 31, 2024
Accepted: March 6, 2024
Article in press: March 6, 2024
Published online: March 28, 2024
Processing time: 94 Days and 0.8 Hours
Peer-review started: December 25, 2023
First decision: January 27, 2024
Revised: January 31, 2024
Accepted: March 6, 2024
Article in press: March 6, 2024
Published online: March 28, 2024
Processing time: 94 Days and 0.8 Hours
Core Tip
Core Tip: Crohn’s disease (CD) is a chronic inflammatory disease of the digestive tract, and approximately one out of four children develop stricturing CD (SCD) requiring intervention. Since strictures tend to recur postoperatively regardless of treatment modality and the estimated lifetime risk of surgery in patients with childhood SCD remains high, new emerging strategies may help to improve the outcomes and overall quality of life of patients with SCD.