Li MM, Zhang Y, Sun F, Huai MX, Zhang FY, Qu CY, Shen F, Li ZH, Xu LM. Feasibility and efficacy of endoscopic purse-string suture-assisted closure for mucosal defects induced by endoscopic manipulations. World J Gastroenterol 2023; 29(4): 731-743 [PMID: 36742166 DOI: 10.3748/wjg.v29.i4.731]
Corresponding Author of This Article
Lei-Ming Xu, MD, Chief Doctor, Professor, Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, No. 1665 Kongjiang Road, Shanghai 200092, China. xuleiming@xinhuamed.com.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Ming-Ming Li, Yi Zhang, Fang Sun, Man-Xiu Huai, Fei-Yu Zhang, Chun-Ying Qu, Feng Shen, Zheng-Hong Li, Lei-Ming Xu, Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
Author contributions: Li MM and Zhang Y contributed equally to this work; Li MM and Zhang Y drafted the manuscript and analyzed the data; Xu LM and Zhang Y designed the study and supervised its implementation; Xu LM, Zhang Y, Qu CY, and Shen F completed the endoscopic manipulations; Sun F, Huai MX, Zhang FY and Li ZH, participated in the experiments; and all authors made critical revisions and approved the final version to be published.
Supported bythe National Natural Science Foundation of China, No. 82172737 and 82003277; and Shanghai Municipal Education Commission, No. 16411950403 and 19411951605.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee at Xinhua Hospital (approval number: XHEC-C-2018-109), Shanghai Jiaotong University School of Medicine.
Informed consent statement: Informed consent was obtained from all individual participants included in the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at xuleiming@xinhuamed.com.cn. Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lei-Ming Xu, MD, Chief Doctor, Professor, Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, No. 1665 Kongjiang Road, Shanghai 200092, China. xuleiming@xinhuamed.com.cn
Received: October 16, 2022 Peer-review started: October 16, 2022 First decision: November 17, 2022 Revised: November 27, 2022 Accepted: January 9, 2023 Article in press: January 9, 2023 Published online: January 28, 2023 Processing time: 96 Days and 3.8 Hours
Core Tip
Core Tip: Endoscopic purse-string assisted suturing (EPSS) has proven to be an effective and safe technique for the closure of large mucosal defects. Endoscopic pre-purse-string suture (P-EPSS) is recently introduced and offers several advantages over conventional endoscopic purse-string suture (C-EPSS). We found that the novel method could offer several advantages over C-EPSS. This retrospective observational study included a total of 180 patients who underwent P-EPSS (n = 63) or C-EPSS (n = 117), and evaluate the feasibility and efficacy of P-EPSS-assisted closure in different clinical situations. In conclusion, EPSS could achieve secure complete closure of mucosal defect. P-EPSS could shorten the procedure and yield complete closure of mucosal defects rather than the C-EPSS closure-type.
