Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 7, 2022; 28(37): 5457-5468
Published online Oct 7, 2022. doi: 10.3748/wjg.v28.i37.5457
Efficacy of endoscopic ultrasound in the evaluation of small gastrointestinal stromal tumors
Qi-Chao Ge, Yu-Fan Wu, Zi-Ming Liu, Zhe Wang, Sheng Wang, Xiang Liu, Nan Ge, Jin-Tao Guo, Si-Yu Sun
Qi-Chao Ge, Yu-Fan Wu, Zi-Ming Liu, Sheng Wang, Xiang Liu, Nan Ge, Jin-Tao Guo, Si-Yu Sun, Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Zhe Wang, Department of Pathology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Author contributions: Ge QC wrote a majority portion of manuscript, prepared the figures and tables, and performed statistical analysis; Wu YF collected the data of patients; Liu ZM helped with the statistical analysis and manuscript writing; Wang Z provided and confirmed the pathological data of all the patients; Wang S, Liu X, and Ge N took part in the design of the study outline and performed tumor dissection; Guo JT and Sun SY were responsible for the revision of the manuscript for important intellectual content and supervised the study; all the authors read and gave their final approval for the manuscript to be submitted.
Supported by National Natural Science Foundation of China, No. 81900601; The University Innovation Team and Innovative Talent Support Program of Liaoning Province, No. LR2019073; and Shenyang Young and Middle-aged Science and Technology Innovation Talent Support Program, No. RC200438.
Institutional review board statement: This study was approved by the Ethics Review Committee of Shengjing Hospital of China Medical University, No. 2022PS009K.
Informed consent statement: All the individual involved gave their informed consent prior to study inclusion.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Tao Guo, MD, PhD, Professor, Department of Gastroenterology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110004, Liaoning Province, China. guojt@sj-hospital.org
Received: June 22, 2022
Peer-review started: June 22, 2022
First decision: September 2, 2022
Revised: September 14, 2022
Accepted: September 20, 2022
Article in press: September 20, 2022
Published online: October 7, 2022
Processing time: 98 Days and 23.1 Hours
Core Tip

Core Tip: Endoscopic ultrasound (EUS) has been the recommended follow-up method for small gastrointestinal stromal tumors (GISTs); however, it is not clear whether positive EUS features can predict the malignant potential of small GISTs. Besides, undergoing close follow-up is an economic and mental burden on patients with small GISTs. This study illustrates an optimal cut-off value for the tumor size (1.48 cm) of small GISTs and uses heterogeneity to evaluate risk prediction. Overall, small GISTs with diameters > 1.48 cm with positive EUS features should receive more intensive follow-up or undergo endoscopic surgery.